Team

(LBA) Laboratoire de Biomécanique Appliquée (UMRT24-AMU/Université Gustave Eiffel)

Laboratory description :

The Laboratoire de Biomécanique Appliquée (LBA, directed by Pierre-Jean Arnoux) is a joint University Gustave Eiffel/Aix-Marseille University research unit (UMRT 24). LBA is located on the North Medical Campus in Marseille and is unique in its multidisciplinary approach involving engineering and medicine for the biomechanical studies of the behavior of the human body in impact situations. Its research activities combine clinical and anatomical knowledge: experimental and theoretical approaches to study the behavior of tissues and structures of the human body (use of cadavers donated for scientific research), modelling and digital simulations. These research topics are devoted to one scientific objective and one single priority: the development of Virtual Human models that sustain the development of new knowledge on trauma events and their effects on the human body, trauma prevention, with the design of safety systems and injury management, including the design of medical devices. These research studies are regularly carried out within the framework of national projects (ANR Blanc, ANR VTT, ANR TechSan, DSCR), or in European projects (Humos, EEVC, APROSYS, CASPER). Affiliated to the surgical department of Marseille North Hospital and to the LBA, the surgical research and educational centre (named CERC in French) directed by Pr. S. Berdah is an experimental platform that uses animal models to facilitate experimental surgical research and development of news surgical tools.

Location : Faculté de Médecine Nord, Marseille

Website: https://lba.univ-gustave-eiffel.fr/

Keywords: Numerical simulations, virtual human, biological material characterization

(CRMBM) Centre de Résonance Magnétique Biologique et Médicale

Laboratory description :

The Centre de Résonance Magnétique Biologique et Médicale (formerly directed by M. Bernard, now directed by M. Guye since 2024) is located on the university hospital campus of La Timone in Marseille. It is affiliated with the CNRS and the University of Aix-Marseille (UMR 7339), and has a long-term agreement with the AP-HM (Assistance Publique-Hôpitaux de Marseille).

The CRMBM's researches are mainly dedicated to developments in Magnetic Resonance Imaging and Spectroscopy (MRI/MRS) and their applications to study pathologies of the central nervous system, cardiovascular system and neuromuscular system, with a transfer strategy involving animal models (rodent models of human pathologies) and human models.

The CRMBM is equipped with 7T and 11.75T MR systems for preclinical studies, and 3T and 7T MR systems for clinical research.

The CRMBM has been involved in spinal cord research since 2007, with initial MR developments dedicated to spinal cord imaging in mice and spinal cord injury models. Current researches focus on the development of quantitative imaging techniques (structure, perfusion, metabolism, etc.) and post-processing tools (segmentation, atlas, etc.), dedicated to a better characterization of spinal cord tissue damage. These methodologies are being applied to various neurodegenerative and traumatic pathologies.

Location:https://crmbm.univ-amu.fr/acces/

Website: https://crmbm.univ-amu.fr/topic/spinal-cord-imaging/

Keywords: Magnetic Resonance Imaging (MRI), quantitative MRI, structure, perfusion, atlases